Objective NMT Monitoring in the ICU

Drug-induced neuromuscular blockade is often used in anesthesia to enable endotracheal intubation, optimize surgical conditions, and assist with mechanical ventilation in patients who have reduced lung performance. Neuromuscular blocking drugs, or agents (NMBAs), act by inhibiting signal transduction at the motor end plate, thus resulting in reversible paralysis of skeletal muscles. The use of NMBAs…

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Sugammadex vs Neostigmine: How the Effective Use of Sugammadex Reduces Costs

Sugammadex vs Neostigmine: How the Effective Use of Sugammadex Reduces Costs Postoperative residual curarization (PORC) frequently occurs following anesthesia and may be associated with the development of pulmonary complications, such as labored breathing, hypoxemia, and aspiration pneumonia. It may also result in a postoperative reduction in muscle strength that can cause an increase in recovery…

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The Cost of Postoperative Respiratory Adverse Events

The Cost of Postoperative Respiratory Adverse Events Respiratory impairment following general anaesthesia can pose a significant problem. Adverse and critical respiratory events (AREs and CREs) have been responsible for increased morbidity and mortality. The main cause of AREs after surgery is related to the use of neuromuscular blockers (NMBAs) during general anaesthesia. The action of…

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Why Quantitative NMT Monitoring is Critical in Surgical Patients and How Best to Do It

Why Quantitative NMT Monitoring is Critical in Surgical Patients and How Best to Do It Some sort of assessment of neuromuscular transmission (NMT) is necessary in surgical patients by clinicians and anesthetists to get a feel for the depth of anesthesia. This assessment can be done using simple yet subjective clinical parameters or through more…

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